1401880-84-9Relevant academic research and scientific papers
Palladium-Catalyzed Direct Synthesis of Phenanthridones from Benzamides through Tandem N–H/C–H Arylation
Banerji, Biswadip,Chatterjee, Satadru,Chandrasekhar,Nayan, Chinmay,Killi, Sunil Kumar
, p. 5214 - 5218 (2017/09/29)
We report a palladium-catalyzed method for the direct synthesis of phenanthridones from benzamides in a single step. Unlike previous reports, the current protocol does not need any directing groups or any harsh conditions. This methodology has a wide functional group tolerance therefore a series of phenanthridones were synthesized with a yield up to 87 %. The efficacy of this protocol was further explored by synthesizing some important naturally occurring amaryllidaceae alkaloids in a single step with very good yields.
Palladium-catalyzed annulation of benzynes with N-substituted-N-(2- halophenyl)formamides: Synthesis of phenanthridinones
Yang, Yuan,Huang, Hui,Wu, Lijun,Liang, Yun
supporting information, p. 5351 - 5355 (2014/07/21)
A novel and efficient procedure for the synthesis of N-substituted phenanthridinones via palladium-catalyzed annulation of benzynes with N-substituted-N-(2-halophenyl)formamides has been developed. This methodology constructs two new C-C bonds via an arylation/annulation process, and provides the desired products in good yields. This journal is the Partner Organisations 2014.
Palladium-catalyzed annulation of arynes by o-halobenzamides: Synthesis of phenanthridinones
Lu, Chun,Dubrovskiy, Anton V.,Larock, Richard C.
, p. 8648 - 8656 (2012/11/07)
The palladium-catalyzed annulation of arynes by substituted o-halobenzamides produces N-substituted phenanthridinones in good yields. This methodology provides this important heterocyclic ring system in a single step by simultaneous C-C and C-N bond formation, under relatively mild reaction conditions, and tolerates a variety of functional groups.
