Actinomycin I, also known as dactinomycin, is a naturally occurring cytotoxic antibiotic derived from the bacterium Streptomyces parvulus. It is a member of the actinomycin family of compounds, characterized by a cyclic peptide structure with a phenoxazone chromophore. Actinomycin I is known for its antineoplastic properties, as it intercalates into DNA, inhibiting RNA synthesis and ultimately leading to cell death. It has been used in the treatment of various cancers, particularly Wilms' tumor and Ewing's sarcoma, and is also employed as a research tool to study DNA-protein interactions. The compound's mechanism of action involves binding to the guanine-cytosine rich regions of DNA, which disrupts the DNA's double helix structure and interferes with the transcription process.

1402-60-4

Post Buying Request

Basic information
1. Product Name: Actinomycin I
2. Synonyms: ActinomycinD, 3A-(4-hydroxy-L-proline)-;1H-Pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecine, actinomycin D deriv.;3H-Phenoxazine, actinomycin D deriv.; Actinomycin X0b
3. CAS NO:1402-60-4
4. Molecular Formula: C62H86 N12 O17
5. Molecular Weight: 0
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: Actinomycin I(CAS DataBase Reference)
10. NIST Chemistry Reference: Actinomycin I(1402-60-4)
11. EPA Substance Registry System: Actinomycin I(1402-60-4)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 1402-60-4(Hazardous Substances Data)

Suppliers
Usage
Upstream product
Downstream Products

1402-60-4 Suppliers

Recommended suppliers

1402-60-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1402-60-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,0 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1402-60:
(6*1)+(5*4)+(4*0)+(3*2)+(2*6)+(1*0)=44
44 % 10 = 4
So 1402-60-4 is a valid CAS Registry Number.

1402-60-4Upstream product

1402-60-4Downstream Products

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1402-60-4