140209-46-7Relevant academic research and scientific papers
Synthesis of 3'-ethynylthymidine, 3'-vinylthymidine and 3'-bromovinylthymidine as potential antiviral agents
Sahlberg
, p. 679 - 682 (2007/10/02)
The synthesis of three novel 3'-unsaturated carbon analogues of AZT and FLT is described. The key step in the synthesis is a Cu(I)-catalyzed addition of vinylmagnesium bromide to a 2,3-unsaturated lactone, followed by, in the case of compounds 2 and 3, el
