140209-88-7Relevant articles and documents
Novel guanidine-containing molecular transporters based on lactose scaffolds: Lipophilicity effect on the intracellular organellar selectivity
Biswas, Goutam,Jeon, Ock-Youm,Lee, Woo Sirl,Kim, Dong-Chan,Kim, Kyong-Tai,Lee, Suho,Chang, Smighoe,Chung, Sung-Kee
experimental part, p. 9161 - 9168 (2009/10/01)
We have synthesized two lactose-based molecular transporters, each containing seven guanidine residues attached to the lactose scaffold through ω-aminocarboxylate linker chains of two different lengths, and have examined their cellular uptakes and intrace
An easy regio- and stereoselective synthesis of a versatile trisaccharide precursor for synthetic carbohydrate based vaccines
Mesa, Juan A.,Tacoronte, Juan E.,Garcia, Ernesto,Leyva, Jorge
, p. 411 - 416 (2008/09/19)
The trisaccharide allyl 2-deoxy-2-phthalimido-6-0-[4-O-(2,3,4,6-tetra-0- benzoyl-β-D-galactopyranosyl)-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl] -β-D-glucopyranoside (3) was prepared directly from acceptor allyl 2-deoxy-2-phthallmido-β-D-glucopyranoside (l)
Synthesis of β-D-Glcp-(1→3)-[β-D-Glcp-(1→6)]-β-D- Glcp-(1→3)-β-D-Glcp-(1→6)-[β-D-Galp-(1→4) -β-D-Glcp-(1→3)]-β-D-GlcpOLauryl, an oligosaccharide with anti-tumor activity
Mei, Xiangdong,Heng, Linsen,Fu, Mingkun,Li, Zhimin,Ning, Jun
, p. 2345 - 2351 (2007/10/03)
A concise and effective synthesis of lauryl heptasaccharide 17 was achieved from the key intermediates lauryl 2,3,4,6-tetra-O-benzoyl-β-D- galactopyranosyl-(1→4)-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl- (1→3)-2,4-di-O-benzoyl-β-D-glucopyranoside (10) and i
Synthesis and hemolytic activity of some hederagenin diglycosides
Chwalek, Martin,Ple, Karen,Voutquenne-Nazabadioko, Laurence
, p. 965 - 971 (2007/10/03)
Glycosylation of hederagenin with the trichloroacetimidate derivatives of six commercial disaccharides (D-cellobiose, D-lactose, D-maltose, D-melibiose, D-gentiobiose, D-isomaltose) was performed giving the protected saponins in high yields. Deprotection
Gold glyconanoparticles: Synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies
Barrientos, Africa G.,De la Fuente, Jesus M.,Rojas, Teresa C.,Fernandez, Asuncion,Penades, Soledad
, p. 1909 - 1921 (2007/10/03)
A simple and versatile methodology is described for tailoring sugar-functionalised gold nanoclusters (glyconanoparticles) that have 3D polyvalent carbohydrate display and globular shapes. This methodology allows the preparation of glyconanoparticles with biologically significant oligosaccharides as well as with differing carbohydrate density. Fluorescent glyconanoparticles have been also prepared for labelling cells in biological tests. The materials are water soluble, stable under physiological conditions and present an exceptional small core size. All of them have been characterised by 1H NMR, UV and IR spectroscopy, TEM and elemental analysis. Their highly polyvalent network can mimic glycosphingolipid clustering and interactions at the plasma membrane, providing an controlled system for glycobiological studies. Furthermore, they are useful building blocks for the design of nanomaterials.