140225-07-6

Upstream product

• 132639-37-3 tert-butyl (E)-4-(2',2'-dibromo-3'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate 
• 132639-34-0 tert-Butyl (E,4S)-2,2-dimethyl-4-(2'-phenylvinyl)-3-oxazolidine-3-carboxylate 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 132639-36-2 tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate 
• 132639-31-7 tert-butyl (E)-4-(2',2'-dibromo-3'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate 
• 132652-65-4 tert-butyl 2,2-dimethyl-4-[(E)-2-phenylethenyl]-1,3-oxazolane-3-carboxylate 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 132639-30-6 tert-butyl (E)-4-(2'-phenylcyclopropyl)-2,2-dimethyl-3-oxazolidinecarboxylate 

Downstream Products

• 132639-33-9 (2R,1'R,2'R,E)-α-(2-Phenylcyclopropyl)glycine hydrochloride 
• 132639-33-9 (2S,1'S,2'S,E)-α-(2-Phenylcyclopropyl)glycine hydrochloride 
• 132697-90-6 (E)-α-(2-phenylcyclopropyl)glycine hydrochloride 

Relevant academic research and scientific papers

SYNTHESIS OF ASYMMETRIC (E)-α-GLYCINES FROM SERINE BY DIASTEREOSELECTIVE DIBROMOCYCLOPROPANATION

An asymmetric synthesis of (E)-α-2-phenylcyclopropyl)glycines and also of a homolog of allocoronamic acid, namely (E)-α-(2-ethylcyclopropyl)glycine, is reported.The key step is the dibromocyclopropanation of tert-butyl (E, 4R)- or (E, 4S)-2,2-dimethyl-4-

Synthesis of asymmetric (E)-α-(2-phenylcyclopropyl)glycines

An asymmetric synthesis of (E)-α-(2-phenylcyclopropyl)glycines is reported. The key step is the dibromocyclopropanation of tert-Butyl (E,4R) or (E,4S)-2,2-dimethyl-4-(2'-phenylvinyl)-3-oxazolidinecarboxylates, easily prepared from L or D-serine, respectiv