1402406-47-6

Basic information

• Product Name: (R)-2-(cyclopentyloxy)-1-methoxy-4-(1-nitrobut-3-en-2-yl)benzene
• Synonyms: (R)-2-(cyclopentyloxy)-1-methoxy-4-(1-nitrobut-3-en-2-yl)benzene
• CAS NO: 1402406-47-6
• Molecular Weight: 291.347
• Mol File: 1402406-47-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-(cyclopentyloxy)-1-methoxy-4-(1-nitrobut-3-en-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(cyclopentyloxy)-1-methoxy-4-(1-nitrobut-3-en-2-yl)benzene(1402406-47-6)
• EPA Substance Registry System: (R)-2-(cyclopentyloxy)-1-methoxy-4-(1-nitrobut-3-en-2-yl)benzene(1402406-47-6)

Safety Data

• Hazardous Substances Data: 1402406-47-6(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 

Downstream Products

• 1402406-56-7 (R)-3-(3-(cyclopentyloxy)-4-methoxyphenyl)-4-nitrobutan-1-ol 
• 1021867-92-4 3-(3-cyclopentyloxy-4-methoxy-phenyl)-4-nitro-butyric acid methyl ester 
• 85416-75-7 (R)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one 

Relevant articles and documents

Regio- and enantioselective palladium-catalyzed allylic alkylation of nitromethane with monosubstituted allyl substrates: Synthesis of (R)-rolipram and (R)-baclofen

The Pd-catalyzed asymmetric allylic alkylation (AAA) reaction of nitromethane with monosubstituted allyl substrates was realized for the first time to provide corresponding products in high yields with excellent regio- and enantioselectivities. The protocol was applied to the enantioselective synthesis of (R)-baclofen and (R)-rolipram.