1402452-36-1Relevant academic research and scientific papers
Generation of 1-aroxyisoquinolines via a silver-catalyzed reaction of 2-alkynylbenzaldoxime with phenol in the presence of p-toluenesulfonyl chloride
Xiao, Qing,Zheng, Danqing,Ding, Qiuping,Wu, Jie
supporting information, p. 5119 - 5122 (2013/06/27)
A silver-catalyzed reaction of 2-alkynylbenzaldoxime with phenol promoted by p-toluenesulfonyl chloride leads to 1-aroxyisoquinolines in good yields. The presence of p-toluenesulfonyl chloride as an activator is essential for the successful transformation
AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with α,β-unsaturated carbonyl compounds
Ding, Qiuping,Wang, Dan,Luo, Puying,Liu, Meiling,Pu, Shouzhi,Zhou, Liyun
supporting information, p. 1949 - 1956 (2013/10/22)
AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with various α,β-unsaturated carbonyl compounds under mild conditions are described, which provides a facile and efficient pathway for the synthesis of 1-alkylated isoquinoline derivatives. The m
Palladium-catalyzed C-H oxidation of isoquinoline N-oxides: Selective alkylation with dialkyl sulfoxides and halogenation with dihalo sulfoxides
Yao, Bo,Song, Ren-Jie,Liu, Yan,Xie, Ye-Xiang,Li, Jin-Heng,Wang, Meng-Ke,Tang, Ri-Yuan,Zhang, Xing-Guo,Deng, Chen-Liang
, p. 1890 - 1896 (2012/09/22)
A novel palladium-catalyzed C-H oxidation of isoquinoline N-oxides has been developed for regioselectively synthesizing substituted isoquinolines. The method represents the first example of using dialkyl sulfoxides as the alkyl sources for the construction of 1-alkylated isoquinolines. Moreover, the regioselective halogenation of isoquinoline N-oxides is also successful using dihalo sulfoxides as the halide sources. Copyright
One-pot two-step synthesis of 1-position arylated 1,3-disubstituted isoquinoline N-oxides
Ding, Qiuping,Wang, Dan,Sang, Xiaoyan,Lin, Yuqing,Peng, Yiyuan
supporting information, p. 8869 - 8874 (2012/10/29)
A one-pot two-step reaction of 2-alkynylbenzaldoximes with aryl halides has been developed, which offers the 1-position arylated 1,3-disubstituted isoquinoline N-oxides in moderate to good yields in most cases. The isoquinoline N-oxide intermediate was pr
Silver triflate catalyzed reaction of 2-alkynylbenzaldoxime with phenol: A general and facile route to 1-aroxyisoquinolines
Zheng, Danqing,Wang, Zhiyong,Wu, Jie
supporting information; experimental part, p. 2810 - 2816 (2011/10/31)
2-Alkynylbenzaldoxime reacts with phenol under the catalysis of silver triflate in the presence of bromo-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBroP) under mild conditions, leading to the formation of 1-aroxyisoquinolines in good to excellent
