1402465-89-7

Basic information

• Product Name: (R)-1-(2-chlorophenyl)ethyl (4-(4-aminophenyl)-1-methyl-1H-pyrazol-5-yl)carbamate
• Synonyms: (R)-1-(2-chlorophenyl)ethyl (4-(4-aminophenyl)-1-methyl-1H-pyrazol-5-yl)carbamate
• CAS NO: 1402465-89-7
• Molecular Weight: 370.838
• Mol File: 1402465-89-7.mol

Chemical Properties

• CAS DataBase Reference: (R)-1-(2-chlorophenyl)ethyl (4-(4-aminophenyl)-1-methyl-1H-pyrazol-5-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(2-chlorophenyl)ethyl (4-(4-aminophenyl)-1-methyl-1H-pyrazol-5-yl)carbamate(1402465-89-7)
• EPA Substance Registry System: (R)-1-(2-chlorophenyl)ethyl (4-(4-aminophenyl)-1-methyl-1H-pyrazol-5-yl)carbamate(1402465-89-7)

Safety Data

• Hazardous Substances Data: 1402465-89-7(Hazardous Substances Data)

Upstream product

• 1402465-80-8 (R)-1-(2-chlorophenyl)ethyl (4-(4-(tert-butoxycarbonylamino)phenyl)-1-methyl-1H-pyrazol-5-yl)carbamate 
• 1402465-77-3 (R)-1-(2-chlorophenyl)ethyl 4-bromo-1-methyl-1H-pyrazol-5-ylcarbamate 
• 13524-04-4 (R)-1-(o-chlorophenyl)ethanol 

Downstream Products

• 1402466-07-2 (R)-3-(4'-(5-(((1-(2-chlorophenyl)ethoxy)carbonyl)amino)-1-methyl-1H-pyrazol-4-yl)-[1,1'-biphenyl]-4-yl)propanoic acid methyl ester 
• 1402465-29-5 (R)-3-(4'-(5-(((1-(2-chlorophenyl)ethoxy)carbonyl)amino)-1-methyl-1H-pyrazol-4-yl)-[1,1'-biphenyl]-4-yl)propanoic acid 
• 1402466-52-7 (R)-1-(2-chlorophenyl)ethyl (4-(4-bromophenyl)-1-methyl-1H-pyrazol-5-yl)carbamate 

Relevant articles and documents

AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS

The present invention relates to compounds of general formula (I) inhibiting lysophosphatidic acid receptor 1 (LPA1), particularly the invention relates to compounds that are Ami do cyclohexane acid derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.

COMPOSITIONS AND METHODS FOR MODULATING LPA RECEPTORS

The present invention relates to compounds of Formula (1), or pharmaceutically acceptable salts thereof and their pharmaceutical compositions, wherein variables are as defined herein, which are useful as modulators of the activity of lysophosphatidic acid (LPA).