1402569-42-9

Basic information

• Product Name: methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2,4,5-trifluorophenyl)-butanoate
• Synonyms: methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2,4,5-trifluorophenyl)-butanoate
• CAS NO: 1402569-42-9
• Molecular Weight: 358.165
• Mol File: 1402569-42-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2,4,5-trifluorophenyl)-butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2,4,5-trifluorophenyl)-butanoate(1402569-42-9)
• EPA Substance Registry System: methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2,4,5-trifluorophenyl)-butanoate(1402569-42-9)

Safety Data

• Hazardous Substances Data: 1402569-42-9(Hazardous Substances Data)

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 1260029-44-4 (E)-4-(2,4,5-trifluoro-phenyl)-but-2-enoic acid methyl ester 
• 1352613-28-5 2,4,5-trifluorobenzene magnesium chloride 
• 367-23-7 1,2,4-trifluorobenzene 

Relevant articles and documents

?-boration of alkene and alkyne intermediates

The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.

?-BORATION OF ALKENE AND ALKYNE INTERMEDIATES

The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis pharmaceutically active agents such as sitagliptin.

PREPARATION OF SITAGLIPTIN INTERMEDIATES

The invention relates to the preparation of chiral compounds, in particular to the preparation of chiral compounds which may be used as intermediates for the preparation of anti-diabetic agents, preferably sitagliptin.