1402573-65-2Relevant academic research and scientific papers
Stereoselective preparation of cyclobutanes with four different substituents: Total synthesis and structural revision of pipercyclobutanamide a and piperchabamide G
Liu, Renhe,Zhang, Min,Wyche, Thomas P.,Winston-Mcpherson, Gabrielle N.,Bugni, Tim S.,Tang, Weiping
, p. 7503 - 7506 (2012/09/10)
Squared away: A general strategy was developed for the diastereo- and enantioselective synthesis of cyclobutanes having four different substituents (see scheme). The strategy involves a RhII-catalyzed cyclopropanation, a AgI-catalyzed regioselective and stereospecific ring expansion, and a RhI-catalyzed addition reaction. The structures of pipercyclobutanamide A and piperchabamide G were synthesized and revised. Copyright
