1402834-93-8Relevant articles and documents
Enantioselective allylation of imines catalyzed by newly developed (-)-β-pinene-based π-allylpalladium catalyst: An efficient synthesis of (R)-α-propylpiperonylamine and (R)-pipecolic acid
Fernandes, Rodney A.,Nallasivam, Jothi L.
, p. 7789 - 7800 (2013/04/23)
A newly developed π-allylpalladium with a (-)-β-pinene framework and an isobutyl side chain catalyzed the enantioselective allylation of imines in good yields and enantioselectivities (20 examples, up to 98% ee). An efficient enantioselective synthesis of the (R)-α-propyl piperonylamine part of DMP 777, a human leukocyte elastase inhibitor and (R)-pipecolic acid have been achieved as a useful application of this methodology. The Royal Society of Chemistry 2012.
