1402839-07-9

Upstream product

• 2142-70-3 2-iodoacetophenone 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 1402839-08-0 3-(tert-butyldimethylsilyloxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-one 
• 1402837-23-3 (S)-5-((S)-2-hydroxyl(cyclohexylethyl))-5H-imidazo[5,1-a]isoindole 
• 1402839-10-4 (1R,3R)-3-(tert-butyldimethylsilyloxy)-3-cyclohexyl-1-(2-iodophenyl)propan-1-ol 
• 1402839-11-5 1-((1S,3S)-3-(tert-butyldimethylsilyloxy)-3-cyclohexyl-1-(2-iodophenyl)propyl)-1H-imidazole 
• 1402839-27-3 (S)-5-((S)-2-(tert-butyldimethylsilyloxy)-2-cyclohexylethyl)-5H-imidazo[5,1-α]isoindole 

Relevant academic research and scientific papers

FUSED IMIDAZOLE DERIVATIVES USEFUL AS IDO INHIBITORS

Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated inimunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.