1402852-69-0

Basic information

• Product Name: (5S,6R,9S)-bis(2,2,2-trifluoroethyl) 2-(3,4-dichlorophenyl)-6-(2-methoxyphenyl)-4-oxo-9-vinyl-3-oxa-1-azaspiro[4.4]non-1-ene-7,7-dicarboxylate
• Synonyms: (5S,6R,9S)-bis(2,2,2-trifluoroethyl) 2-(3,4-dichlorophenyl)-6-(2-methoxyphenyl)-4-oxo-9-vinyl-3-oxa-1-azaspiro[4.4]non-1-ene-7,7-dicarboxylate
• CAS NO: 1402852-69-0
• Molecular Weight: 668.374
• Mol File: 1402852-69-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5S,6R,9S)-bis(2,2,2-trifluoroethyl) 2-(3,4-dichlorophenyl)-6-(2-methoxyphenyl)-4-oxo-9-vinyl-3-oxa-1-azaspiro[4.4]non-1-ene-7,7-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (5S,6R,9S)-bis(2,2,2-trifluoroethyl) 2-(3,4-dichlorophenyl)-6-(2-methoxyphenyl)-4-oxo-9-vinyl-3-oxa-1-azaspiro[4.4]non-1-ene-7,7-dicarboxylate(1402852-69-0)
• EPA Substance Registry System: (5S,6R,9S)-bis(2,2,2-trifluoroethyl) 2-(3,4-dichlorophenyl)-6-(2-methoxyphenyl)-4-oxo-9-vinyl-3-oxa-1-azaspiro[4.4]non-1-ene-7,7-dicarboxylate(1402852-69-0)

Safety Data

• Hazardous Substances Data: 1402852-69-0(Hazardous Substances Data)

Upstream product

• 1402852-63-4 (Z)-2-(3,4-dichlorophenyl)-4-(2-methoxybenzylidene)oxazol-5(4H)-one 
• 104883-33-2 malonic acid di(2,2,2-trifluoroethyl ester) 
• 17321-80-1 2-(3,4-dichlorobenzamido)acetic acid 
• 135-02-4 ortho-anisaldehyde 

Relevant articles and documents

Palladium-catalyzed diastereo- and enantioselective formal [3 + 2]-cycloadditions of substituted vinylcyclopropanes

We describe a palladium-catalyzed diastereo- and enantioselective formal [3 + 2]-cycloaddition between substituted vinylcyclopropanes and electron-deficient olefins in the form of azlactone- and Meldrums acid alkylidenes to give highly substituted cyclopentane products. By modulation of the electronic properties of the vinylcyclopropane and the electron-deficient olefin, high levels of stereoselectivity were obtained. The remote stereoinduction afforded by the catalyst, distal from the chiral pocket generated by the ligand, is proposed to be the result of a new mechanism invoking the Curtin-Hammett principle.