1402929-33-2Relevant academic research and scientific papers
Highly enantioselective hetero-diels-alder reaction of 1,3-bis(silyloxy)-1, 3-dienes with aldehydes catalyzed by chiral disulfonimide
Guin, Joyram,Rabalakos, Constantinos,List, Benjamin
supporting information; experimental part, p. 8859 - 8863 (2012/10/08)
Bulking up with F: The title reaction proceeds using 1 mol % of the new perfluoroisopropyl chiral disulfonimide catalyst 1 to deliver several 2,6-disubstituted and 2,5,6-trisubstituted dihydropyrones in good yields and with excellent enantiomeric ratios. The utility of this methodology is illustrated with the first enantioselective synthesis of a potent aromatase inhibitor. Copyright
