1403165-41-2Relevant academic research and scientific papers
Syn-selective asymmetric mannich reaction of sulfonyl imines with iminoesters catalyzed by the N,N,N-tridentate bis(imidazolidine)pyridine (PyBidine)-Cu(OTf)2 complex
Arai, Takayoshi,Mishiro, Asami,Matsumura, Eri,Awata, Atsuko,Shirasugi, Mayu
, p. 11219 - 11222 (2012/11/07)
Chiral ligand: The [PyBidine-Cu(OTf)2] (Tf= trifluoromethanesulfonate) complex catalyzed the asymmetric Mannich reaction of sulfonyl imines and iminoesters to give the products in a high syn-selective manner. For both 4-toluene (Ts)- and 4-nitrophenylsulfonyl (Ns)-imines, the syn-adducts were obtained in up to 99 % ee (see scheme). Copyright
