1403227-97-3

Basic information

• Product Name: (1R,3S,4R)-3-(3,5-bis(trifluoromethyl)benzyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
• Synonyms: (1R,3S,4R)-3-(3,5-bis(trifluoromethyl)benzyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
• CAS NO: 1403227-97-3
• Molecular Weight: 378.358
• Mol File: 1403227-97-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,3S,4R)-3-(3,5-bis(trifluoromethyl)benzyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S,4R)-3-(3,5-bis(trifluoromethyl)benzyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one(1403227-97-3)
• EPA Substance Registry System: (1R,3S,4R)-3-(3,5-bis(trifluoromethyl)benzyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one(1403227-97-3)

Safety Data

• Hazardous Substances Data: 1403227-97-3(Hazardous Substances Data)

Upstream product

• 473929-46-3 (1R,4R)-3-[(E)-(dimethylamino)methylidene]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 

Downstream Products

• 1403228-10-3 (1R,4S,5S)-4-(3,5-bis(trifluoromethyl)benzyl)-1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-2-one 
• 1403228-13-6 (1R,4S,5S)-4-(3,5-bis(trifluoromethyl)benzyl)-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane 
• 1403228-15-8 (1R,4S,5S)-4-(3,5-bis(trifluoromethyl)benzyl)-1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-ium chloride 

Relevant articles and documents

Synthesis and structural characterization of novel camphor-derived amines

Two novel 4-substituted camphidine derivatives 10a,b have been prepared from (+)-camphor (1) in five steps, the Beckmann rearrangement being the bottleneck of the synthesis. Isoborneol derivative 5b, formed as a side product during the hydrogenation of arylidene ketone 3b, under Beckmann rearrangement conditions yielded interesting novel rearrangement products 11 and 12. (1S)-(+)-Camphorquinone (13) was transformed into diamines 15 and 16 in two steps, the former being cyclized into an imidazoline salt 17, an N-heterocyclic carbene precursor. The structures of all novel compounds have been meticulously characterized using NMR techniques and/or single crystal X-ray analysis. Copyright