1403265-16-6

Basic information

• Product Name: 184B-43-1
• Synonyms: 184B-43-1
• CAS NO: 1403265-16-6
• Molecular Weight: 907.014
• Mol File: 1403265-16-6.mol

Chemical Properties

• CAS DataBase Reference: 184B-43-1(CAS DataBase Reference)
• NIST Chemistry Reference: 184B-43-1(1403265-16-6)
• EPA Substance Registry System: 184B-43-1(1403265-16-6)

Safety Data

• Hazardous Substances Data: 1403265-16-6(Hazardous Substances Data)

Upstream product

• 7580-85-0 tert-butyl glycidyl ether 

Relevant articles and documents

Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use

Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.