1403333-23-2

Upstream product

• 845306-08-3 tert-butyl 5-bromopyridine-2-carboxylate 
• 30766-11-1 5-bromoisonicotinic acid 
• 1403333-26-5 tert-butyl 3,3'-bipyridine-6-carboxylate 
• 1297540-77-2 (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chloro-6-fluorobenzonitrile 
• 1214339-84-0 3,3'-bipyridine-6-carboxylic acid 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 1297540-76-1 2-chloro-6-fluoro-4-(1H-pyrazol-3-yl)benzonitrile 
• 1692-25-7 3-pyridylboronic acid 

Relevant academic research and scientific papers

ANDROGEN RECEPTOR MODULATING CARBOXAMIDES

Compounds of formula (I) or (II) wherein Rx, Rz, R9, R10, R14, R14′, R15, R15′, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

ANDROGEN RECEPTOR MODULATING CARBOXAMIDES

Compounds of formula (I) wherein Rx, Rz, R9, R10, R14, R14', R15, R15', A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.