1403362-05-9Relevant articles and documents
Total synthesis of the core tetrasaccharide of the lipopolysaccharide from Neisseria meningitidis
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, (2013/04/10)
The present invention relates to the total synthesis of the α-GlcNAc-(1→2)-α-Hep-(1→3)-α-Hep-(1→5)-α-Kdo core tetrasaccharide of the lipopolysaccharide from Neisseria meningitidis, the resulting product obtained by the total synthesis and α-GlcNAc-(1→2)-α-Hep-(1→3)-α-Hep-(1→5)-α-Kdo for use as a vaccine for immunization against diseases caused by infection with bacteria containing the tetrasaccharide, especially for immunization against meningitis, septicaemia, pneumonia and nasopharyngitis caused by Neisseria meningitidis.