1403387-35-8

Usage

Molecular structure

A complex molecular structure with a boron atom bonded to an oxygen atom and a phenyl ring with a methylcyclopropyl substituent.

Functional groups

Contains multiple tert-butyl and tetramethyl groups attached to the phenyl ring.

Application in organic synthesis

Potential use in the formation of carbon-carbon and carbon-heteroatom bonds.

Pharmaceutical research

May have uses in pharmaceutical research.

Advanced materials production

Possible application in the production of advanced materials.

Further study and development

Could lead to new and valuable applications in various fields.

Upstream product

• 1403387-37-0 1-bromo-3-(tert-butyl)-5-(1-methylcyclopropyl)benzene 
• 73183-34-3 bis(pinacol)diborane 
• 129316-09-2 1,3-dibromo-5-t-butylbenzene 
• 1403387-36-9 1-bromo-3-(tert-butyl)-5-(prop-1-en-2-yl)benzene 

Downstream Products

• 1561964-72-4 methyl 4-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexylmethyl)-1-methyl-1H-pyrrole-2-carboxylate 
• 1561964-93-9 methyl 5-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-4-(cyclohexylmethyl)-1H-pyrrole-2-carboxylate 
• 1561965-46-5 methyl 4-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexanecarbonyl)-1-methyl-1H-pyrrole-2-carboxylate 
• 1561965-55-6 ethyl 5-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-1-(cyclohexylmethyl)-1H-pyrazole-3-carboxylate 
• 1561964-75-7 4-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexylmethyl)-1-methyl-1H-pyrrole-2-carboxylic acid 
• 1561964-95-1 5-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-4-(cyclohexylmethyl)-1H-pyrrole-2-carboxylic acid 
• 1561958-56-2 5-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-4-(cyclohexylmethyl)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrrole-2-carboxamide 
• 1561965-26-1 methyl 4-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-3-chloro-5-(cyclohexylmethyl)-1-methyl-1H-pyrrole-2-carboxylate 
• 1561965-49-8 4-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexanecarbonyl)-1-methyl-1H-pyrrole-2-carboxylic acid 
• 1561965-57-8 5-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-1-(cyclohexylmethyl)-1H-pyrazole-3-carboxylic acid 
• 1561965-88-5 potassium 1-(3-(tert-butyl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexyloxy)-1H-pyrazole-3-carboxylate 

Relevant academic research and scientific papers

CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide containing cyclic compounds of Formula (1) to Formula (5) and the enantiomers, diastereomers, tautomers, /V-oxides, solvates and pharmaceutically acceptable salts thereof.

CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA]

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administering these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides carboxamide or sulfonamide containing cyclic compounds of Formula (1), (1'), (100), (100'), (200) and (200') and the enantiomers, diastereomers, tautomers, /V-oxides, solvates and pharmaceutically acceptable salts thereof.

PYRROLO SULFONAMIDE COMPOUNDS FOR MODULATION OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORGAMMA, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administrating these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo sulfonamide compounds of Formula (1) and the enantiomers, diastereomers, tautomers, solvates and pharmaceutically acceptable salts thereof.