1403387-81-4

Basic information

• Product Name: 4-bromo-2-(1-methylcyclopropyl)benzene-1-sulfonyl chloride
• Synonyms: 4-bromo-2-(1-methylcyclopropyl)benzene-1-sulfonyl chloride
• CAS NO: 1403387-81-4
• Molecular Weight: 309.611
• Mol File: 1403387-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-(1-methylcyclopropyl)benzene-1-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-(1-methylcyclopropyl)benzene-1-sulfonyl chloride(1403387-81-4)
• EPA Substance Registry System: 4-bromo-2-(1-methylcyclopropyl)benzene-1-sulfonyl chloride(1403387-81-4)

Safety Data

• Hazardous Substances Data: 1403387-81-4(Hazardous Substances Data)

Upstream product

• 1403387-80-3 4-bromo-2-(1-methylcyclopropyl)aniline 
• 71759-33-6 1-methyl-1-(o-aminophenyl)cyclopropane 
• 40088-87-7 1-methyl-1-(o-nitrophenyl)cyclopropane 
• 2214-14-4 (1-methylcyclopropyl)benzene 
• 98-83-9 isopropenylbenzene 

Downstream Products

• 1403387-82-5 4-bromo-N-(tert-butyl)-2-(1-methylcyclopropyl)benzenesulfonamide 
• 1403387-79-0 N-(tert-butyl)-2-(1-methylcyclopropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide 

Relevant articles and documents

PYRROLO SULFONAMIDE COMPOUNDS FOR MODULATION OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORGAMMA, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administrating these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo sulfonamide compounds of Formula (1) and the enantiomers, diastereomers, tautomers, solvates and pharmaceutically acceptable salts thereof.