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1403460-12-7

17β-(3-carboxylpropionylamino)-androst-1,4-diene-3-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1403460-12-7 Structure

  • Basic information

    1. Product Name: 17β-(3-carboxylpropionylamino)-androst-1,4-diene-3-one
    2. Synonyms: 17β-(3-carboxylpropionylamino)-androst-1,4-diene-3-one
    3. CAS NO:1403460-12-7
    4. Molecular Formula:
    5. Molecular Weight: 401.503
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1403460-12-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 17β-(3-carboxylpropionylamino)-androst-1,4-diene-3-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 17β-(3-carboxylpropionylamino)-androst-1,4-diene-3-one(1403460-12-7)
    11. EPA Substance Registry System: 17β-(3-carboxylpropionylamino)-androst-1,4-diene-3-one(1403460-12-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1403460-12-7(Hazardous Substances Data)

1403460-12-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1403460-12-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,3,4,6 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1403460-12:
(9*1)+(8*4)+(7*0)+(6*3)+(5*4)+(4*6)+(3*0)+(2*1)+(1*2)=107
107 % 10 = 7
So 1403460-12-7 is a valid CAS Registry Number.

1403460-12-7Downstream Products

1403460-12-7Relevant articles and documents

Development of three-component conjugates: To get nano-globes with porous surfaces, high in vivo anti-osteoporosis activity and minimal side effects

Kang, Guifeng,Wang, Yuji,Liu, Jiawang,Wu, Jianhui,Zhao, Ming,Li, Guochun,Li, Ning,Peng, Li,Zhang, Xiaoyi,Li, Li,Mair, Nathan,Peng, Shiqi

, p. 21740 - 21748 (2012)

Three novel three-component conjugates of a succinyl spacer, a pharmacophore of 17β-amino-11α-hydroxyl-androst-1,4-diene-3-one, and a targeting sequence of RGD-tetrapeptide (peptide Arg-Gly-Asp-AA) were designed, synthesized, and evaluated. This paper presents evidence that inserting a succinyl functional group into the pharmacophore and the targeting sequence improves the oral anti-osteoporosis activities in mouse glucocorticoid model of secondary osteoporosis, which were reflected by dry weight, ash weight, Ca 2+ and bone mineral content of the femur of examined mice. These novel conjugates have no side effects on estrogen, and form nano-globes with a porous surface. This paper emphasizes that the hydrogen bond between the carbonyl group of the succinyl group and the carboxylic group of the C-terminal amino acid residue of RGD-tetrapeptides is the key to forming pores on the surface of the nano-globes of these novel conjugates.

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