1403475-02-4Relevant academic research and scientific papers
Potassium: Tert -butoxide mediated aerobic hydroxylation of arylboronic acids: An application towards the synthesis of (E)-phenoxy acrylates
Muhammad, Ibrahim,Balakrishnan, Madasamy Hari,Sasidharan, Manickam,Mannathan, Subramaniyan
, p. 11065 - 11068 (2019)
The first example of potassium tert-butoxide mediated aerobic hydroxylation of arylboronic acids is described. A variety of arylboronic acids bearing both electron donating and withdrawing substituents successfully participated in the reaction and furnished phenols in good yields. This strategy also provides access to one pot synthesis of (E)-3-phenoxy acrylates from arylboronic acids and propiolates. The solvent plays an important role and a binary solvent system comprising CH3CN/THF is found to be the best.
Stereoselective synthesis of (E)-?-aryloxyl and alkyloxyl acrylates through DABCO-catalysed Michael additions of phenols and alcohols to ethyl 2,3-butadienoate
Wei, Feng,Haibo, Wu,Houjun, Qian,Zhengyi, Li,Xiaoqiang, Sun,Zhiming, Wang
, p. 364 - 367 (2016/07/06)
The development of DABCO-catalysed Michael addition of phenols and alcohols to ethyl 2,3-butadienoate provides an efficient synthetic pathway to (E)-?-aryloxyl and alkyloxyl acrylates in i-PrOH or under solvent-free conditions. The major advantages of the present method are wide substrate scope, mild reaction conditions, high stereoselectivity, and good reaction yields.
Enantioselective synthesis of β-aryloxycarboxylic esters via asymmetric hydrogenation of β-aryloxy-α,β-unsaturated esters
Stewart, Gavin W.,Yamagata, Adam D. Gammack,Gibson, Andrew W.,Keen, Stephen P.,Scott, Jeremy P.,Shevlin, Michael
supporting information, p. 5440 - 5443,4 (2012/12/12)
A novel synthesis of β-aryloxycarboxylic esters via asymmetric hydrogenation of the corresponding β-aryloxy-α,β-unsaturated esters has been demonstrated. Bis(norbornadiene)rhodium(I) tetrafluoroborate (1 mol %) and Walphos W008-1 were used to generate the
