1403477-46-2Relevant academic research and scientific papers
Magnesium-Catalyzed Stereoselective Hydrostannylation of Internal and Terminal Alkynes
Magre, Marc,Szewczyk, Marcin,Rueping, Magnus
supporting information, p. 1594 - 1598 (2020/02/22)
A regio- and stereoselective magnesium-catalyzed hydrostannylation of internal and terminal alkynes has been developed. Excellent yields and selectivities are obtained for a wide range of terminal and internal symmetrical and unsymmetrical alkynes by usin
On the hydrostannylation of aryl propargylic alcohols and their derivatives: Remarkable differences in both regio- and stereoselectivity in radical- and nonradical-mediated transformations
Oderinde, Martins S.,Froese, Robert D. J.,Organ, Michael G.
supporting information, p. 8579 - 8583 (2014/07/21)
Herein, we describe a highly regio- and stereoselective radical-mediated and molecular-oxygen (O2)-dependent hydrostannylation of phenyl propargylic alcohols and their derivatives. There is a significant steric effect on the stereoselectivity of the tin-radical addition. Further, the uncatalyzed regio- and stereoselective hydrostannylation of aryl propargylic alcohols with nBu3SnH and Ph3SnH is also described and occurs with near titration kinetics. Although the uncatalyzed addition with nBu3SnH gave a remarkable γ-regioselectivity irrespective of the electronic nature of the aryl moiety, addition with Ph3SnH appears to be driven by the electronic nature of the aryl alkynes.
