1403596-35-9

Upstream product

• 27007-53-0 methyl-2-bromo-5-chlorobenzoate 
• 1403596-34-8 methyl 2-bromo-5-chloro-3-((tetrahydro-2H-pyran-4-yl)amino)benzoate 
• 75-07-0 acetaldehyde 
• 1403596-33-7 methyl 3-amino-2-bromo-5-chlorobenzoate 
• 1403596-31-5 methyl 2-bromo-5-chloro-3-nitrobenzoate 

Downstream Products

• 1403591-14-9 2-bromo-5-chloro-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yI)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)benzamide 
• 1403596-36-0 2-bromo-5-chloro-3-[ethyl(oxan-4-yl)amino]benzoic acid 

Relevant academic research and scientific papers

ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS

This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

SUBSTITUTED BENZENE COMPOUNDS

The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.