1403599-36-9

Basic information

• Product Name: (R)-6-[(S)-1-(benzyloxy)propyl]-1,2,3,6-tetrahydropyridine
• Synonyms: (R)-6-[(S)-1-(benzyloxy)propyl]-1,2,3,6-tetrahydropyridine
• CAS NO: 1403599-36-9
• Molecular Weight: 231.338
• Mol File: 1403599-36-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-6-[(S)-1-(benzyloxy)propyl]-1,2,3,6-tetrahydropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-6-[(S)-1-(benzyloxy)propyl]-1,2,3,6-tetrahydropyridine(1403599-36-9)
• EPA Substance Registry System: (R)-6-[(S)-1-(benzyloxy)propyl]-1,2,3,6-tetrahydropyridine(1403599-36-9)

Safety Data

• Hazardous Substances Data: 1403599-36-9(Hazardous Substances Data)

Upstream product

• 1403599-33-6 benzyl (3R,4S)-4-(benzyloxy)-1-phenylhex-1-en-3-ylcarbamate 
• 1403599-35-8 (3R,4S)-4-(benzyloxy)-N-(but-3-enyl)-1-phenylhex-1-en-3-amine 
• 1403599-34-7 (3R,4S,Z)-4-(benzyloxy)-1-phenylhex-1-en-3-amine 

Downstream Products

• 495-20-5 (S)-1-[(R)-piperidin-2-yl]propan-1-ol [(-)-α-conhydrine] 

Relevant articles and documents

Stereoselective synthesis of (-)-α-conhydrine and its pyrrolidine analogue

The stereoselective synthesis of (-)-α-conhydrine and its pyrrolidine analogue was achieved from readily available D-erythronolactone. The key step of this synthesis includes a highly regioselective and diastereoselective addition of chlorosulfonyl isocyanate to 1,2-anti-dibenzyl ether to afford the 1,2-anti-amino alcohol. The total synthesis of (-)-α-conhydrine and its pyrrolidine analogue starting from readily available D-erythronolactone was achieved via the regioselective and diastereoselective allylic amination of anti-1,2-dibenzyl ether by using chlorosulfonyl isocyanate.