1403778-24-4Relevant articles and documents
Photochemical generation of oxa-dibenzocyclooctyne (ODIBO) for metal-free click ligations
McNitt, Christopher D.,Popik, Vladimir V.
, p. 8200 - 8202,3 (2012)
Oxa-dibenzocyclooctynes (ODIBO, 2a-c) are prepared by photochemical decarbonylation of corresponding cyclopropenones (photo-ODIBO, 1a-c). While photo-ODIBO does not react with azides, ODIBO is one of the most reactive cyclooctynes exhibiting rates of cycloaddition over 45 M-1 s -1 in aqueous solutions. ODIBO is stable under ambient conditions and has low reactivity towards thiols. Photo-ODIBO survives heating up to 160 °C and does not react with thiols.