14038-08-5

Usage

Uses

Used in Dye and Pigment Synthesis:
2,4-DINITRO-2'-METHOXYDIPHENYLAMINE is used as an intermediate in the synthesis of dyes and pigments, contributing to the production of various colorants for different industries.
Used in Nitrocellulose Stabilization:
2,4-DINITRO-2'-METHOXYDIPHENYLAMINE is used as a stabilizer for nitrocellulose, enhancing the performance and stability of this material in various applications.
Used in High-Energy Explosive Production:
2,4-DINITRO-2'-METHOXYDIPHENYLAMINE is used as a raw material in the production of high-energy explosives, playing a crucial role in the development of powerful explosive compounds.

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 99-65-0 meta-dinitrobenzene 
• 70-34-8 2,4-Dinitrofluorobenzene 

Downstream Products

• 571150-40-8 N¹-(2-methoxy-phenyl)-4-nitro-o-phenylenediamine 
• 106166-34-1 1-(2-methoxy-phenyl)-5-nitro-1H-benzotriazole 
• 380641-63-4 5-amino-1-(2-methoxyphenyl)benzimidazole 
• 6358-23-2 2-hydroxy-2',4'-dinitrodiphenylamine 

Relevant academic research and scientific papers

Reaction of 2,4-Dinitrofluorobenzene with o-Anisidine in Benzene. Further Evidence of the "Dimer" Mechanism

The reaction of 2,4-dinitrofluorobenzene with o-anisidine (B) in benzene exhibits a quadratic dependence of the observed second-order rate coefficient, kA, with , and similar behavior is found in the reaction with p-anisidine, as was previou

Synthesis and Anti-Staphylococcal Activity of 2,4-Disubstituted Diphenylamines

Infections caused by Staphylococcus aureus are ubiquitous and life threatening. Evolution of resistant strains has necessitated the need to continuously discover new drugs to combat such organisms. Diphenyl ethers, such as triclosan, have recently shown potential as antibacterial agents. In this study, a series of diphenyl amines were synthesized and evaluated for in vitro antibacterial activity against Gram-positive (Staphylococcus aureus, Bacillus subtilis, Staphylococcus epidermidis) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Pseudomonas putida) bacteria. Preliminary results showed that six of the twelve synthesized molecules were active against Staphylococcus aureus. Most notable amongst them were compounds 2(2,4-dinitrophenylamino) phenol and 2(2-dinitrophenylamino)phenol having minimum inhibitory concentration (MIC) in the range of 7.8-15.6 μg mL-1 and 7.8-62.5 μg mL-1 respectively for all the eight selected organisms. Five active compounds from the preliminary results were further screened against resistant S. aureus cultures where compounds 2(2,4-dinitrophenylamino)phenol, 2(2-dinitrophenylamino)phenol and 2-chloro-N-(2-(2,4-dichlorophenylamino)phenyl)acetamide gave encouraging results having MIC in the range 3.9-7.8 μg mL-1 for most of the organisms. Results obtained above for the selected organisms and the resistant S. aureus strains conclude that hydroxyl group at 2-position of ring B potentiates the antibacterial activity and overcomes the antibiotic resistance.

Oxidative arylamination of 1,3-dinitrobenzene and 3-nitropyridine under anaerobic conditions: The dual role of the nitroarenes

1,3-Dinitrobenzene and 3-nitropyridine react with lithium arylamides under anaerobic conditions to produce N-aryl-2,4-dinitroanilines and N-aryl-5-nitropyridin-2-amines, respectively, in 8-42% yields. ARKAT-USA, Inc.

SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION

Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate, solvate or N-oxide thereof. R1 is independently hydrogen or (C1-C6)alkyl; R2 is independently hydrogen, (C1-C6)alkyl, aryl, or heteroaryl; R2' is independently hydrogen, (C1-C6)alkyl, CF3 or C2F5; R3 is independently (C1-C6)alkyl, aryl, 2-tetrahydrofuryhnethyl, an aliphatic tertiary amine, or 4-methoxybenzyl; or R2 and R3 may be joined together to form a 5 or 6 member ring lactone; R4 is independently hydrogen, (C1-C6)alkyl, a 2- or 4-R5-substituted aromatic ring selected from a 4-R5-phenyl or a 2-R5-5-pyridyl, aryl, heteroaryl, aliphatic tertiary amine or halogen; and R5, R5', R6, R6', R7, R7' are each independently hydrogen, (C1-C6)alkyl, aryl, optionally substituted phenyl, heteroaryl, a heterocyclic ring, an aliphatic tertiary amine, or halogen.

15N NMR and FTIR studies of 2,4-dinitroanilines and their salts

Twenty-two 2,4-dinitroanilines were synthesised and their pK(a) values were determined. The 2,4-dinitroanilines and their protonated forms were studied by 15N NMR spectroscopy. The relations between the 15N NMR chemical shifts and the pK(a) values of the 2,4-dinitroanilines and their salts were found to be linear. The deprotonation reaction of N-methyl-2,4- dinitroanilines and N-methyl-2,4,6-trinitroaniline by MTBD was successful only for the latter and yielded protonated MTBD molecule and the anion in which the electrons are strongly delocalised. The kinetic parameters of the 2,4-dinitroanilines in reactions with hydroxide ions in mixed solvent DMSO:water (95:5, v/v) were determinated and discussed. (C) 2000 Elsevier Science B.V.