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1403815-38-2

7-(2-chlorophenylamino)-5-((2-[18F]fluoroethyoxy)methyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1403815-38-2 Structure

  • Basic information

    1. Product Name: 7-(2-chlorophenylamino)-5-((2-[18F]fluoroethyoxy)methyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
    2. Synonyms:
    3. CAS NO:1403815-38-2
    4. Molecular Formula:
    5. Molecular Weight: 344.765
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1403815-38-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-(2-chlorophenylamino)-5-((2-[18F]fluoroethyoxy)methyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-(2-chlorophenylamino)-5-((2-[18F]fluoroethyoxy)methyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile(1403815-38-2)
    11. EPA Substance Registry System: 7-(2-chlorophenylamino)-5-((2-[18F]fluoroethyoxy)methyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile(1403815-38-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1403815-38-2(Hazardous Substances Data)

1403815-38-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1403815-38-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,3,8,1 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1403815-38:
(9*1)+(8*4)+(7*0)+(6*3)+(5*8)+(4*1)+(3*5)+(2*3)+(1*8)=132
132 % 10 = 2
So 1403815-38-2 is a valid CAS Registry Number.

1403815-38-2Downstream Products

1403815-38-2Relevant articles and documents

Synthesis and biological evaluation of 7-(2-Chlorophenylamino)-5-((2-[ 18F]fluoro-ethyoxy)methyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile as PET tumor imaging agent

Xu, Jingli,Liu, Hang,Li, Guixia,He, Yong,Ding, Rui,Wang, Xiao,Feng, Man,Zhang, Shuting,Chen, Yurong,Li, Shilei,Zhao, Mingxia,Li, Yingruo,Qi, Chuanmin

, p. 827 - 834,8 (2020/08/31)

An 18F-labeled pyrazolo[1,5-a]pyrimidine derivative, 7-(2-chlorophenylamino)-5-((2-[18F] fluoroethyoxy)methyl)pyrazolo[1, 5-a]pyrimidine-3-carbonitrile ([18F]5), has been designed and prepared as a radio tracer candidate for tumor detection with positron emission tomography (PET). The desired product [18F]5 was synthesized by nucleophilic substitution of the corresponding tosylated precursor with [ 18F]KF=Kryptofix 2.2.2 and potassium carbonate in anhydrous DMF at 100 °C for 20 min followed by purification with HPLC. The radiochemical purity was >98%, and the radio-chemical yield was 25% (decay-uncorrected). Compound [18F]5 was very stable in vitro. The biodistribution study in mice bearing S180 tumors demonstrated that [18F]5 had a rapid and prolonged accumulation in tumors with moderate washout from other tissues.

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