1403876-99-2Relevant academic research and scientific papers
Nucleolytic property promoted by biologically active metal-based complexes formed by neutral quatridentate ligands: Synthesis, characterization, and DNA binding studies
Pothiraj,Baskaran,Raman
, p. 1192 - 1203 (2012)
A series of Ni(II), Cu(II), and Zn(II) complexes have been synthesized and characterized with physicochemical and spectral techniques. Absorption titration study of the interaction of the complexes with calf-thymus (CT) DNA has shown that the complexes can bind to CT DNA. The cyclic voltammograms of all the complexes recorded in the presence of CT DNA-buffer solution have shown that they can bind to CT DNA via intercalation mode, which has also been verified by the viscosity experiments. The antimicrobial and DNA cleavage activities of all the compounds have also been investigated.
Nucleolytic property promoted by biologically active metal-based complexes formed by neutral quatridentate ligands: Synthesis, characterization, and DNA binding studies
Pothiraj, K.,Baskaran, T.,Raman, N.
, p. 1192 - 1203,12 (2012/12/12)
A series of Ni(II), Cu(II), and Zn(II) complexes have been synthesized and characterized with physicochemical and spectral techniques. Absorption titration study of the interaction of the complexes with calf-thymus (CT) DNA has shown that the complexes can bind to CT DNA. The cyclic voltammograms of all the complexes recorded in the presence of CT DNA-buffer solution have shown that they can bind to CT DNA via intercalation mode, which has also been verified by the viscosity experiments. The antimicrobial and DNA cleavage activities of all the compounds have also been investigated.
