1403980-56-2Relevant academic research and scientific papers
Sensing acetylcholine and anticholinesterase compounds
Schena, Alberto,Johnsson, Kai
, p. 1302 - 1305 (2014)
Acetylcholine is a key neurotransmitter, and anticholinesterase agents are essential compounds used as medical drugs, pesticides, and chemical warfare agents. A semisynthetic fluorescence-based probe for the direct, real-time detection of acetylcholine and anticholinesterase compounds is introduced. The probe possesses good sensitivity, tunable detection range, and can be selectively targeted to cell surfaces, thereby making it an attractive tool for applications in analytical chemistry and quantitative biology.
Semisynthetic fluorescent sensor proteins based on self-labeling proteintags
Brun, Matthias A.,Tan, Kui-Thong,Nakata, Eiji,Hinner, Marlon J.,Johnsson, Kai
supporting information; experimental part, p. 5873 - 5884 (2009/09/24)
Genetically encoded fluorescent sensor proteins offer the possibility toprobe the concentration of key metabolites in living cells. The approac hes currently used to generate such fluorescent sensor proteins lack generality, as they require a protein that
