1404111-05-2Relevant academic research and scientific papers
Ligand promoted and controlled palladium-catalyzed intramolecular Heck reaction of homoallyl alcohols: A facile synthesis of cyclopentaannulated quinolines
Singh, Radhey M.,Chandra, Atish,Sharma, Neha,Singh, Bhawana,Kumar, Ritush
, p. 9206 - 9210 (2012)
Bidentate phosphine ligands in palladium-catalyzed intramolecular Heck reactions of 2-chloroquinolin-3-yl-(1-homoallyl)alcohols are described to afford facile synthesis of 3-methylene-2,3-dihydro-1H-cyclopenta[b]quinolines in improved yields. We further observed using bulky aromatic phosphine ligand in Pd-catalyzed intermolecular Heck coupling reaction at olefinic centers with iodobenzene also favored exclusively Heck products in excellent yield.
