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140412-85-7

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140412-85-7 Usage

General Description

10-methyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepine-2-carbonitrile is a chemical compound with a complex molecular structure. It is a carbonitrile derivative and contains a dibenzo[b,f][1,4]oxazepine ring system. 10-methyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepine-2-carbonitrile is also known as bis-10,11-dihydro-11-oxo-10-methyl-dibenzo[b,f][1,4]oxazepine-2-carbonitrile and is used in the synthesis and chemical research. It may have potential pharmaceutical properties due to its unique structure, and further studies may be needed to explore its potential applications in various fields such as medicine and materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 140412-85-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,4,1 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 140412-85:
(8*1)+(7*4)+(6*0)+(5*4)+(4*1)+(3*2)+(2*8)+(1*5)=87
87 % 10 = 7
So 140412-85-7 is a valid CAS Registry Number.

140412-85-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-6-oxobenzo[b][1,4]benzoxazepine-8-carbonitrile

1.2 Other means of identification

Product number -
Other names 2-Cyano-10-methyl-dibenz(b,f)(1,4)oxazepin-11-(10H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:140412-85-7 SDS

140412-85-7Downstream Products

140412-85-7Relevant articles and documents

Novel Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. 2. Tricyclic Pyridobenzoxazepinones and Dibenzoxazepinones

Klunder, Janice M.,Hargrave, Karl D.,West, MaryAnn,Cullen, Ernest,Pal, Kollol,et al.

, p. 1887 - 1897 (2007/10/02)

Dibenzoxazepin-11(10H)-ones (III), pyridobenzoxazepin-6(5H)-ones (IV), and pyridobenzoxazepin-5(6H)-ones (V) were found to inhibit human immunodeficiency virus type 1 reverse transcriptase with IC50 values as 19 nM.A-ring substitution has a profound effect on activity, with appropriate substituents at the positions ortho and para to the lactam nitrogen providing dramatically enhanced potency.Substitution in the C-ring is generally neutral or detrimental to activity.Although a C-ring amino substituent at the position meta to the lactam carbonyl is generally beneficial to activity, it has essentially no effect when the A-ring is optimally substituted.Like the dipyridodiazepinone nevirapine, compounds III-V are specific for HIV-1 RT, exhibiting no inhibitory activity against HIV-2 RT or other virial reverse transcriptase enzymes.

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