1404202-53-4

Upstream product

• 16629-19-9 thiophene-2-sulfonyl chloride 
• 63069-48-7 p-chloro-o-iodoaniline 

Downstream Products

• 1447159-67-2 N-(1-allyl-5-methoxy-1H-indol-2-yl)-N-(4-chloro-2-iodophenyl)thiophene-2-sulfonamide 
• 1447159-61-6 N-(1-allyl-5-nitro-1H-indol-2-yl)-N-(4-chloro-2-iodophenyl)thiophene-2-sulfonamide 
• 1447159-64-9 N-(1-allyl-5-cyano-1H-indol-2-yl)-N-(4-chloro-2-iodophenyl)thiophene-2-sulfonamide 
• 1447159-71-8 N-(4-chloro-2-(1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)phenyl)thiophene-2-sulfonamide 
• 1447159-82-1 N-(4-chloro-2-(7-chloro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)phenyl)thiophene-2-sulfonamide 
• 1447159-83-2 N-(4-chloro-2-(7-nitro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)phenyl)thiophene-2-sulfonamide 
• 1447159-84-3 N-(2-(7-bromo-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)-4-chlorophenyl)thiophene-2-sulfonamide 
• 1447159-60-5 N-(1-allyl-5-chloro-1H-indol-2-yl)-N-(4-chloro-2-iodophenyl)thiophene-2-sulfonamide 
• 1447159-48-9 N-(1-allyl-1H-indol-2-yl)-N-(4-chloro-2-iodophenyl)thiophene-2-sulfonamide 
• 1447159-62-7 N-(1-allyl-5-bromo-1H-indol-2-yl)-N-(4-chloro-2-iodophenyl)thiophene-2-sulfonamide 

Relevant academic research and scientific papers

Creation of molecular complexities via a new Cu-catalyzed cascade reaction: A direct access to novel 2,2′-spirobiindole derivatives

A Cu-mediated unprecedented cascade reaction in the presence of air afforded a conceptually new synthesis of 2,2′-spirobiindole derivatives. This reaction proceeds via the rearrangement of several bonds in a cyclopenta[b]indole framework including a facial selective intramolecular ring closure. The potential of this method is highlighted in the straightforward and single step synthesis of a paullone like compound. This journal is

AlCl3 mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.