140421-12-1Relevant articles and documents
Preparation of Chiral Aziridines from Chiral Oxiranes with Retention of Configuration
Toshimitsu, Akio,Abe, Hideyuki,Hirosawa, Chitaru,Tanimoto, Shigeo
, p. 284 - 285 (1992)
Chiral oxiranes are converted into chiral aziridines via β-hydroxyalkyl aryl sulfides and then β-tosylaminoalkyl aryl sulfides without loss of optical purity and with overall retention of configuration.
Conversion of Chiral Oxiranes into Chiral Aziridines with Retention of Configuration by Way of Chiral Episulfonium Ions and Reactions of the Aziridines with Grignard Reagents
Toshimitsu, Akio,Abe, Hideyuki,Hirosawa, Chitaru,Tamao, Kohei
, p. 3465 - 3472 (2007/10/02)
Chiral oxiranes are converted into chiral aziridines with overall retention of configuration by means of sulfur chemistry.The key step of this procedure is the transformation of the organosulfur intermediates, i.e., the replacement of a hydroxy group boun