Basic information

Product Name: 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate
Synonyms: 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate
CAS NO:140424-82-4
Molecular Formula: C₂₈H₂₈N₂O₇Si
Molecular Weight: 532.62
EINECS: N/A
Product Categories: Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate(CAS DataBase Reference)
NIST Chemistry Reference: 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate(140424-82-4)
EPA Substance Registry System: 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate(140424-82-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 140424-82-4(Hazardous Substances Data)

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140424-82-4 Usage

Uses

Used in Pharmaceutical Synthesis:
2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate is used as a protected intermediate for the synthesis of 5-Ethyl-2’-deoxyuridine (E915020), a modulator that enhances the antitumor action and pharmacokinetics of 5-Fluorouracil (F596000). This potent antineoplastic agent is widely used in clinical applications for the treatment of various types of cancer.
In the pharmaceutical industry, 2'-Deoxy-5-[(triMethylsilyl)ethynyl]uridine 3',5'-Dibenzoate plays a crucial role in the development of new drugs and the improvement of existing ones. Its unique structure allows for the creation of more effective and targeted therapies, ultimately contributing to the advancement of cancer treatment and other medical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 140424-82-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,4,2 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 140424-82:
(8*1)+(7*4)+(6*0)+(5*4)+(4*2)+(3*4)+(2*8)+(1*2)=94
94 % 10 = 4
So 140424-82-4 is a valid CAS Registry Number.

140424-82-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name	((2R,3S,5R)-3-(benzoyloxy)-5-(2,4-dioxo-5-((trimethylsilyl)ethynyl)-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:140424-82-4 SDS

140424-82-4Upstream product

140424-82-4Downstream Products

107667-10-7 2'-Deoxy-3',5'-di-O-benzoyl-5-ethynyluridine

140424-82-4Relevant academic research and scientific papers

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