14044-59-8

Upstream product

• 13991-20-3 1-(morpholin-4-yl)pent-4-yn-1-one 
• 110-91-8 morpholine 
• 14267-92-6 1-chloro-4-pentyne 
• 2468-55-5 5-iodopent-1-yne 
• 55183-44-3 4-pentynoic chloride 

Downstream Products

• 1046155-05-8 4-[4-(phenylseleno)pent-4-enyl]morpholine 
• 1046155-04-7 4-[4-(phenylthio)pent-4-enyl]morpholine 
• 950736-21-7 N-{3-[3-(5-morpholin-4-ylpent-1-yn-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}-3-(trifluoromethyl)benzamide 
• 912353-72-1 C₂₇H₂₈ClFN₄O₂ 

Relevant academic research and scientific papers

ALKYNYL PYRROLOPYRIMIDINES AND RELATED ANALOGS AS HSP90-INHIBITORS

Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compounds are also described and claimed.

3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors

This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.

Pyrroloquinolones as antiviral agents

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.