1404433-41-5Relevant academic research and scientific papers
Highly diastereo- and enantioselective cyclopropanation of 1,2-disubstituted alkenes
Li, Jun,Liao, Sai-Hu,Xiong, Hu,Zhou, You-Yun,Sun, Xiu-Li,Zhang, Yue,Zhou, Xiao-Guang,Tang, Yong
supporting information; experimental part, p. 8838 - 8841 (2012/10/08)
A helping hand: A series of bis(oxazoline) ligands, which contain pendant C2-symmetry-breaking groups, for the Cu-catalyzed asymmetric cyclopropanation of 1,2-disubstituted alkenes has been developed. Under mild reaction conditions, both cis- and trans-1,2-substituted alkenes can be converted into the corresponding 1,2,3-trisubstituted cyclopropanes with high levels of diastereo- and enantioselectivity (see scheme). Copyright
