1404475-96-2Relevant academic research and scientific papers
Discovery of an l-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100
Kim, Se-Ho,Tangallapally, Rajendra,Kim, In Chul,Trovato, Richard,Parker, Daniel,Patton, J. Scott,Reeves, Leslie,Bradford, Chad,Wettstein, Daniel,Baichwal, Vijay,Papac, Damon,Bajji, Ashok,Carlson, Robert,Yager, Kraig M.
, p. 5254 - 5257 (2015)
Various types of Hsp90 inhibitors have been and continue to undergo clinical investigation. One development candidate is the purine-based, synthetic Hsp90 inhibitor 1 (MPC-3100), which successfully completed a phase I clinical study. However, further clin
PRODRUGS OF THERAPEUTIC COMPOUNDS
-
, (2012/11/13)
The present invention provides compounds, pharmaceutical compositions and medicaments comprising such compounds, and the use of these compounds, compositions, and medicaments in methods of treating diseases and disorders such as cancers.
