1404545-48-7Relevant articles and documents
Oxygen atom transfer mediated by an iron(IV)/iron(II) macrocyclic complex containing pyridine and tertiary amine donors
Ye, Wanhua,Staples, Richard J.,Rybak-Akimova, Elena V.
, p. 1 - 12 (2012)
A new non-heme iron model complex containing a high-spin iron(II) complexed with N-methylated pyridine-containing macrocycle was synthesized and crystallographically characterized. The complex generates peroxo- and high-valent iron-oxo intermediates in reactions with tert-butylhydroperoxide and isopropyl 2-iodoxybenzoate, respectively, allowing to gain insight into the formation and reactivity of enzyme-like intermediates related to biological oxygen activation. The formation and reactivity of these intermediate species were investigated by the stopped-flow methodology. The mechanism of oxygen transfer to organic substrates involving reaction of oxoiron(IV) intermediate was elucidated on the basis of spectroscopic and kinetic data. Incorporation of a pyridine ring into the macrocycle increased the reactivity of the Fe IVO intermediates in comparison with polyamine tetraaza macrocyclic complexes: ferryl (FeIVO) species derived from 3 demonstrated electrophilic reactivity in transferring an oxygen atom to substituted triarylphosphines and to olefins (such as cyclooctene). However, iron(III) alkylperoxo intermediate was unreactive with cyclooctene.
