140455-60-3Relevant academic research and scientific papers
HCV INHIBITORS AND METHODS OF USING THEM
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Page/Page column 22-23, (2010/02/11)
The present invention comprises tetrazoloquinoline-compounds that are inhibitors of HCV. Compositions comprising the compounds in combination with a pharmaceutically acceptable carrier are also disclosed, as are methods of using the compounds and composit
HETEROTRICYCLIC COMPOUNDS FOR USE AS HCV INHIBITORS
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Page/Page column 34, (2008/06/13)
The present invention comprises tetrazoloquinine-compounds that are inhibitors of HCV. Compositions comprising the compounds in combination with a pharmaceutically acceptable carrier are also disclosed, as are methods of using the compounds and compositions to inhibit HCV infection of a cell, particular in the form of treating HCV infection in a mammal.
SYNTHESIS OF 1,2,4-TRIAZOLOQUINOLINE-9-, 1,2,3,4-TETRAZOLOQUINOLINE-9- AND 1,2,4-TRIAZINOQUINOLINE-10-CARBOXYLIC ACIDS FROM 2-CHLORO- AND 2-HYDRAZINOCINCHONINIC ACIDS
Yanborisova, O. A.,Konshin, M. E.
, p. 986 - 988 (2007/10/02)
Treatment of 2-chlorocinchoninic acid with hydrazine gives 2-hydrazinecinchoninic acid and with aroylhydrazines to give 1,2,4-triazoloquinoline-9-carboxylic acids.These are also prepared by the action of benzoyl chloride or the carboxylic acid on 2-hydrazinocinchoninic acid.With pyruvic acid the latter gives 3-methyl-4-oxo-1,2,4-triazinoquinoline-10-carboxylic acid and with nitrous acid gives 1,2,3,4-tetrazoloquinoline-9-carboxylic acid.
