140460-91-9

Upstream product

• 97135-19-8 (+/-)-trans-(10,11)-dihydroxy-8,9,10,11-tetrahydrodibenzacridine 
• 97135-18-7 (+/-)-trans-10,11-dihydroxy-10,11-dihydrodibenzyacridine 
• 140380-84-3 ((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-acetic acid (10R,11R)-10-[2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-acetoxy]-8,9,10,11-tetrahydro-dibenzo[a,h]acridin-11-yl ester 
• 140380-83-2 ((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-acetic acid (10R,11R)-10-[2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-acetoxy]-10,11-dihydro-dibenzo[a,h]acridin-11-yl ester 

Downstream Products

• 140460-96-4 (-)-(8S,9R,10S,11R)-10,11-dihydroxy-8,9-epoxy-8,9,10,11-tetrahydrodibenzacridine 
• 140461-57-0 (+)-(8R,9S,10S,11R)-10,11-dihydroxy-8,9-epoxy-8,9,10,11-tetrahydrodibenzyacridine 
• 140380-85-4 (E)-3-(4-Dimethylamino-phenyl)-acrylic acid (10R,11R)-10-[(E)-3-(4-dimethylamino-phenyl)-acryloyloxy]-8,9,10,11-tetrahydro-dibenzo[a,h]acridin-11-yl ester 

Relevant academic research and scientific papers

Synthesis of Enantiomerically Pure Bay-Region 10,11-Diol 8,9-Epoxide Diastereomers of the Carcinogen Dibenzacridine

The present study describes the synthesis and configurational assignment of four enantiomerically pure, bay-region 10,11-diol 8,9-epoxide diastereomers 14-17 of dibenzacridine (1) from the corresponding optically pure trans-10,11-dihydroxy-10,11-dihy