140479-40-9

Upstream product

• 88023-78-3 para-methoxybenzyl chloride 
• 138436-25-6 (R)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 138436-20-1 (R)-(E)-2-<<(tert-Butyldiphenylsilyl)oxy>methyl>-5-methylhex-3-en-1-ol 
• 24850-33-7 allyltributylstanane 
• 138436-30-3 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-propionaldehyde 

Downstream Products

• 146512-63-2 (4R,5R)-cis-4-allyl-5-((((4-methoxybenzyl)oxy)methoxy)methyl)-2,2-dimethyl-1,3-dioxane 
• 140479-54-5 (4R,5R)-trans-4-allyl-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-1,3-dioxane 
• 140479-50-1 (2R,3R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)hex-5-ene-1,3-diol 
• 146512-61-0 (2S,3R)-2-((((4-methoxybenzyl)oxy)methoxy)methyl)hex-5-ene-1,3-diol 

Relevant academic research and scientific papers

Protecting group controlled diastereoselective allylation of asymmetrized bis (hydroxymethyl) acetaldehydes (BHYMA)

MgBr2 catalysed allylation of a series of diprotected asymmetrized bis (Hydroxymethyl) acetaldehydes 2 with allyltributylstannane proceeds with good diastereoselectivity. The stereochemical results are in line with a cyclic chelated transition state, where only one of the two CH2OR appendages, due to the different nature of protecting groups, is capable of coordinating the Lewis acid.