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1405-87-4

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Bacitracin
Cas No: 1405-87-4
USD $ 400.0-500.0 / Kilogram 1 Kilogram 2000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
Bacitracin Manufacturer/High quality/Best price/In stock
Cas No: 1405-87-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High quality Bacitracin supplier in China
Cas No: 1405-87-4
No Data 1 Kilogram 30 Metric Ton/Month Simagchem Corporation Contact Supplier
Bacitracin
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No Data 1 Kilogram 20 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier
Bacitracin
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Bacitracin
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Bacitracin
Cas No: 1405-87-4
No Data 1 Kilogram 10 Kilogram/Week Hangzhou J&H Chemical Co., Ltd. Contact Supplier
Bacitracin
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No Data No Data Metric Ton/Day Shenzhen READLINE Technology Co., Ltd. Contact Supplier
Bacitracin
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No Data 1 Kilogram 10 Kilogram/Day HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
buy Bacitracin from China supplier factory manufacturer
Cas No: 1405-87-4
USD $ 10.0-10.0 / Kilogram 1 Kilogram 800 Metric Ton/Month Crovell Biotech (Hebei) Co., Ltd. Contact Supplier

1405-87-4 Usage

Uses

antibacterial

Purification Methods

Bacitracin has been purified by carrier displacement using n-heptanol, n-octanol and n-nonanol as carriers and 50% EtOH in 0.1 N HCl. The pure material gives one spot with RF ~0.5 on paper chromatography using AcOH:n-BuOH:H2O (4:1:5). [Porath Acta Chem Scand 6 1237 1952.] It has also been purified by ion-exchange chromatography. It is a white powder soluble in H2O and EtOH but insoluble in Et2O, CHCl3 and Me2CO. It is stable in acidic solution but unstable in base. It is a strong antibacterial. [Abraham & Bewton Biochem J 47 257 1950, Synthesis: Munekata et al. Bull Chem Soc Jpn 46 3187, 3835 1973, Beilstein 27 III/IV 5746.]

Chemical Properties

White to pale buff powder

Uses

Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting depho sphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.

Brand name

Ziba (X Gen).
InChI:InChI=1/C66H103N17O16S/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36?,37?,40-,41+,42+,43-,44+,45-,46-,47+,48?,52-,53-,54-/m0/s1

1405-87-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Bacitracin

1.2 Other means of identification

Product number -
Other names BACIDRIN

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1405-87-4 SDS

1405-87-4Related news

Identification and pathogenicity of an XDR Streptococcus suis isolate that harbours the phenicol-oxazolidinone resistance genes optrA and cfr, and the Bacitracin (cas 1405-87-4) resistance locus bcrABDR09/29/2019

ABSTRACTOne hundred and seven Streptococcus suis isolates were collected from healthy pigs or asymptomatic carriers in Jiangsu, China in 2016–2017. Thirty-eight percent of the isolates were linezolid-resistant and all carried the optrA gene. Among them, one isolate, SFJ44, was resistant to all ...detailed

Incorporation of Bacitracin (cas 1405-87-4) in Langmuir films of phospholipids at the air-water interface09/28/2019

Properties of microbicide drugs are believed to be associated to their interactions with biointerfaces such as cell membranes, encouraging research on the identification of membrane sites capable of drug binding. In this study, we investigated the interaction of bacitracin, a known antibiotic pe...detailed

ProtocolsImmobilizing Bacitracin (cas 1405-87-4) on titanium for prophylaxis of infections and for improving osteoinductivity: An in vivo study10/01/2019

Bacitracin immobilized on the titanium (Ti) surface significantly improves anti-bacterial activity and biocompatibility in vitro. In the current study, we investigated the biologic performance (bactericidal effect and bone-implant integration) of bacitracin-modified Ti in vivo. A rat osteomyelit...detailed

Bacitracin (cas 1405-87-4) promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis09/27/2019

Bacitracin, a widely used metallopeptide antibiotic, has been reported to be locally used in treating wounds without systemic adverse reactions. Our preliminary study showed that bacitracin might enhance the osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMSCs). The pre...detailed

Original ArticleUntangling the transcription regulatory network of the Bacitracin (cas 1405-87-4) synthase operon in Bacillus licheniformis DW209/25/2019

The bacitracin synthetase gene cluster in Bacillus licheniformis DW2 is composed of the bacABC operon encoding a non-ribosomal peptide synthetase and bacT encoding a thioesterase. Although the bacitracin gene cluster has been well studied, little is known about how this gene cluster is regulated...detailed

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