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Zinc bacitracin
Cas No: 1405-89-6
USD $ 2.0-2.0 / Kilogram 1 Kilogram 1-10 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
1405-89-6
Cas No: 1405-89-6
No Data 1 Kilogram 1000 Kilogram/Month Shaanxi WuZhiYuan Biological Technology Co.,Ltd Contact Supplier
Factory supply Best price API 99% Zinc bacitracin Powder
Cas No: 1405-89-6
No Data 1 Kilogram 1000 Kilogram/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
Zinc bacitracin (Bacitracin Zinc) Micronized USP/EP GMP factory price /
Cas No: 1405-89-6
No Data 1 Kilogram 1000 Kilogram/Month Josun International Limited Contact Supplier
Bacitracin Zinc API CAS NO.1405-89-6
Cas No: 1405-89-6
USD $ 1.0-3.0 / Metric Ton 1 Metric Ton 10 Metric Ton/Day Hebei yanxi chemical co.,LTD. Contact Supplier
Zinc Bacitracin
Cas No: 1405-89-6
USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 1-500 Metric Ton/Day Chemwill Asia Co., Ltd. Contact Supplier
CAS:1405-89-6 Zinc bacitracin
Cas No: 1405-89-6
No Data 1 Kilogram 100 Kilogram/Week Kono Chem Co.,Ltd Contact Supplier
Factory high quality Zinc bacitracin Cas 1405-89-6 with favorable price
Cas No: 1405-89-6
USD $ 320.0-325.0 / Kilogram 1 Kilogram 10 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Zinc bacitracin CAS 1405-89-6
Cas No: 1405-89-6
No Data 1 Metric Ton 1 Metric Ton/Day Hefei TNJ chemical industry co.,ltd Contact Supplier
Zinc bacitracin
Cas No: 1405-89-6
No Data 1 Gram 20 Kilogram/Day Henan Allgreen Chemical Co.,Ltd Contact Supplier

1405-89-6 Usage

Uses

1.It is used as feed additive for promoting the growth of livestock and poultry, prevention and treatment of livestock and poultry bacterial diarrhea and dense helicoid is caused by blood dysentery. Oral administration of zinc bacitracin is almost no absorption, mostly in 2 days with the feces. So it is not easy to remain in the livestock and poultry products; bacteria to bacitracin produced very little resistance, and other antibiotics nor cross resistance and with penicillin, streptomycin, neomycin, streptomycin, mostly clay bacteria and have a synergistic effect. This product is toxic, not injection. The goods and olaquindox, guitar mold, mold of Virginia, Pinella mildew element existence is incompatibility.
2.Zinc bacitracin is a polypeptide antibiotic, against gram positive bacteria with a bactericidal effect, its mechanism is mainly inhibiting the synthesis of bacterial cell wall of bacteria, can also with sensitive bacteria cell membrane combined injury of cell membrane integrity, resulting in cells of the important materials in the outflow. Effectively inhibit gram positive bacteria and some gram negative bacteria; bacteria on resistance of zinc bacitracin slower, and other antibiotics without cross resistance.
3.Peptide antibiotics, can inhibit the phosphorylation of pyrophosphate lipid, thereby inhibiting the synthesis of bacterial cell walls.

Bacitracin

Bacillus peptide is extracted from the culture fluid lichenoid (Bacillus licheniformis) is a polypeptide antibiotic. White or light yellow powder, no odor or slight odor and bitter taste, are hygroscopic. Soluble in water and ethanol, unstable, aqueous solution at room temperature is easy to inactivation. When pH < 3, it is easy to precipitate, when pH > 9, it is not stable, after dissolution it should be the refrigerator cold. This product is calculated on the dry goods, potency per milligram of not less than 55 Bacillus peptide units. Bacillus peptide is BacitracinZincSalt, is more stable than bacitracin. It is used as feed additive, which can promote the growth and development of livestock and poultry, prevent intestinal infection, improve feed reward, and so on.
Bacitracin antibiotic is similar to penicillin spectrum, and strong antibacterial effect against gram positive bacteria, there was no significant effect on Gram negative bacteria. For serious infection of Staphylococcus aureus. Does not absorb oral for intestinal infection. Topical against sensitive bacteria caused by skin, mouth, eye infection and inflammation of the breasts, which is also effective. It has damage to the kidney function. Bacitracin zinc has been used as a feed additive drugs. Oral almost not absorbed, it is generally believed that, the livestock products have no drug residues.
This product is a narrow spectrum antibiotics, mainly against most gram positive bacteria, which have a strong antibacterial effect, it is also effectiveto to spirochetes and actinomycetes, but against gram negative bacilli invalid. Several antibiotics such as penicillin G, streptomycin, neomycin, polymyxin and synergistic effect. The zinc salt is mainly for feed additive, can prevent intestinal infection, promote growth, improve feed conversion efficiency. Bacteria develop slow resistance to this product, but this product with other antibiotics are without cross resistance.
This product is toxic and cannot be administered. Oral administration can treat of livestock bacterial diarrhea and pig dense helicoid dysentery. Clinical often several antibiotics such as penicillin, streptomycin, neomycin, polymyxin B combined use of to enhance the effect.
The above information is edited by the Chemicalbook Han Ya.

Feed additives

Zinc bacitracin is bacitracin and zinc ions to form complexes, which is a polypeptide antibiotic, is one of the most widely used antibiotics in feed additives, zinc content is 2%~12%. synthetic product is white or yellowish powder, with special odor, deliquescent alkaline substance, soluble in water, methanol and ethanol. Zinc bacitracin has strong antibacterial effect against gram positive bacteria, also has antibacterial properties of some gram negative bacteria. The use of zinc bacitracin in pig feed, can promote growth, improve feed, prevention and treatment of swine bacterial diarrhea and chronic respiratory diseases. The concentration of 10 in general to 100mg/kg, more than the addition range of effect was not improved obviously. Zinc bacitracin in swine intestine is not generally absorbed, so there is no problem, is a reliable and safe antibiotic additives. Bacitracin zinc toxicity is strong, and not easy to be absorbed, it can not be used as a systemic infection treatment.

Chemical Properties

White to pale buff powder

Brand name

Ziba (X Gen).

Uses

Bacitracin zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.

Role and purpose

Peptide antibiotics have a strong antibacterial effect on the gram positive bacteria, also has antibacterial effect to a small number of Gram-negative bacteria, and the spiral and actinomycetes and resistant to penicillin resistant Staphylococcus aureus.The antibacterial mechanism inhibits for the formation of damage and bacterial cell wall. The bacterial cytoplasmic membrane can promote beneficial intestinal microbial growth, increased intestinal permeability, promote the absorption of nutrients. Mainly used to promote the growth of livestock and poultry, livestock and poultry as well as prevention and treatment of bacterial diarrhea caused by Treponema pig dysentery. Oral administration of zinc bacitracin is almost no absorption, mostly in 2 days with the feces. So it is not easy to remain in the livestock and poultry products; bacteria to bacitracin produced very little resistance, and other antibiotics nor cross resistance and with penicillin, streptomycin, neomycin, streptomycin, mostly clay bacteria and have a synergistic effect. This product is toxic, not injection. The goods and olaquindox, guitar mold, mold of Virginia, Pinella mildew element existence is incompatibility.
InChI:InChI=1/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1

1405-89-6 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1048007)  Bacitracin zinc  United States Pharmacopeia (USP) Reference Standard 1405-89-6 1048007-200MG 4,662.45CNY Detail

1405-89-6Related news

Short communicationDietary enzyme and Zinc bacitracin (cas 1405-89-6) reduce colonisation of layer hens by the intestinal spirochaete Brachyspira intermedia09/30/2019

Brachyspira intermedia strain HB60 was used to experimentally infect 40 individually caged 22-week-old laying hens. Another 10 control birds were sham-inoculated with sterile broth. All chickens received an experimental layer diet based on wheat. The infected birds were randomly divided into fou...detailed

Effect of substitution of medium-chain organic acids for Zinc bacitracin (cas 1405-89-6) in a diet containing colistin on performance and development of intestinal lymphoid tissues in growing rabbits experimentally infected with Escherichia coli O103 and Clostridium perfringens toxinotype A09/27/2019

This work tested the effect of replacing zinc bacitracin with a blend of caproic and caprylic acids in a diet including colistin on growth performance, mortality, gut histology and development of intestinal lymphoid tissues in rabbits experimentally infected with Escherichia coli and Clostridium...detailed

Hops β-acids and Zinc bacitracin (cas 1405-89-6) affect the performance and intestinal microbiota of broilers challenged with Eimeria acervulina and Eimeria tenella09/24/2019

The objective of this study was to evaluate the effects of dietary hops β-acids on the productive performance and intestinal microbiota of broilers challenged with Eimeria acervulina and Eimeria tenella. 1440 broiler chicks were allocated in a randomized design with 6 treatments and 6 replicate...detailed

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