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Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxois a potent polyene antifungal medication that exhibits a broad spectrum of activity against various fungal species, including candida and aspergillus. It functions by binding to ergosterol, a component of the fungal cell membrane, which leads to the disruption of the membrane's structure and the leakage of intracellular contents, ultimately resulting in the death of the fungal cells and clearance of the infection.

1405-90-9

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1405-90-9 Usage

Uses

Used in Antifungal Treatments:
Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxois used as a therapeutic agent for treating severe or systemic fungal infections. It is particularly effective in cases where other antifungal medications have been ineffective, making it a crucial option for managing serious fungal infections that do not respond to alternative therapies.
Used in Severe Fungal Infections:
Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxois used as a last-resort treatment for severe fungal infections that have not responded to other treatments. Its broad-spectrum activity and potent antifungal properties make it a valuable asset in combating life-threatening fungal infections.
However, it is important to note that Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxois also associated with significant toxicities, particularly to the kidneys. As a result, its use is typically reserved for serious fungal infections that do not respond to other therapies, and it is administered with caution to minimize potential adverse effects.

Check Digit Verification of cas no

The CAS Registry Mumber 1405-90-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,0 and 5 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1405-90:
(6*1)+(5*4)+(4*0)+(3*5)+(2*9)+(1*0)=59
59 % 10 = 9
So 1405-90-9 is a valid CAS Registry Number.
InChI:InChI=1/C47H71NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-35(65-47-45(60)42(48)44(59)30(4)64-47)26-39(56)41(46(61)62)38(55)24-34(52)23-37(54)36(53)20-19-31(49)21-32(50)22-33(51)25-40(57)63-29(3)28(2)43(27)58/h5-18,27-30,32-33,35-39,41-45,47,50-51,53-56,58-60H,19-26,48H2,1-4H3,(H,61,62)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27?,28?,29?,30-,32?,33?,35?,36?,37?,38?,39?,41?,42+,43?,44-,45+,47?/m0/s1

1405-90-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (4E,6E,8E,10E,12E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,32,33,35,37-heptahydroxy-18,20,21-trimethyl-23,29-dioxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid

1.2 Other means of identification

Product number -
Other names EINECS 215-788-3

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1405-90-9 SDS

1405-90-9Upstream product

1405-90-9Downstream Products

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