1405-90-9 Usage
General Description
Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxo- is a polyene antifungal medication used to treat a variety of fungal infections. It works by binding to ergosterol, a component of the fungal cell membrane, disrupting its structure and causing leakage of intracellular contents. This leads to the death of the fungal cells and helps to clear the infection. Amphotericin B is known for its broad spectrum of activity against various fungal species, including candida and aspergillus. It is typically used in severe or systemic fungal infections, especially when other antifungal medications have been ineffective. However, it is also associated with significant toxicities, particularly to the kidneys, and is usually reserved for serious fungal infections that do not respond to other therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1405-90-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,0 and 5 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1405-90:
(6*1)+(5*4)+(4*0)+(3*5)+(2*9)+(1*0)=59
59 % 10 = 9
So 1405-90-9 is a valid CAS Registry Number.
InChI:InChI=1/C47H71NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-35(65-47-45(60)42(48)44(59)30(4)64-47)26-39(56)41(46(61)62)38(55)24-34(52)23-37(54)36(53)20-19-31(49)21-32(50)22-33(51)25-40(57)63-29(3)28(2)43(27)58/h5-18,27-30,32-33,35-39,41-45,47,50-51,53-56,58-60H,19-26,48H2,1-4H3,(H,61,62)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27?,28?,29?,30-,32?,33?,35?,36?,37?,38?,39?,41?,42+,43?,44-,45+,47?/m0/s1
