14052-35-8

Basic information

• Product Name: 2,4-cyclohexadien-1-one, 6-[[[3-(dimethylamino)propyl]amino]methylene]-, nickel(2+) salt, (6Z)-
• CAS NO: 14052-35-8
• Molecular Formula: C₂₄H₃₄N₄NiO₂
• Molecular Weight: 471.2605
• Mol File: 14052-35-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 335.3°C at 760 mmHg
• Flash Point: 156.6°C
• Vapor Pressure: 0.000121mmHg at 25°C
• CAS DataBase Reference: 2,4-cyclohexadien-1-one, 6-[[[3-(dimethylamino)propyl]amino]methylene]-, nickel(2+) salt, (6Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-cyclohexadien-1-one, 6-[[[3-(dimethylamino)propyl]amino]methylene]-, nickel(2+) salt, (6Z)-(14052-35-8)
• EPA Substance Registry System: 2,4-cyclohexadien-1-one, 6-[[[3-(dimethylamino)propyl]amino]methylene]-, nickel(2+) salt, (6Z)-(14052-35-8)

Safety Data

• Hazardous Substances Data: 14052-35-8(Hazardous Substances Data)

Usage

Molecular weight

278.29 g/mol

Appearance

Pale green solid

Solubility

Soluble in common organic solvents such as ethanol, methanol, and acetone

Reactivity

Unique reactivity of nickel(2+) salts in various chemical reactions

Stereochemistry

(6Z)designation indicates the stereochemistry of the compound

Potential applications

Catalysis, materials science, organic synthesis, medicinal chemistry, and coordination chemistry

Functional groups

2,4-Cyclohexadien-1-one ring, 6-[[[3-(dimethylamino)propyl]amino]methylene]group, and nickel(2+) salt. The presence of the dimethylamino group could make this compound useful as a ligand in coordination chemistry.

Upstream product

• 90-02-8 salicylaldehyde 
• 109-55-7 1-amino-3-(dimethylamino)propane 
• 36339-86-3 bis(3,6-dimethylsalicylaldehydato)nickel(II) 

Relevant articles and documents

In-situ nickel(II) complexes of 3-(dimethylamino)-1-propylamine based Schiff base ligands: Structural, electrochemical, biomolecular interaction and antimicrobial properties

Five new di-Schiff base nickel(II) complexes (1–5) of salen type ligands were synthesized in-situ by condensation of 3-(dimethylamino)-1-propylamine with 2-hydroxybenzaldehyde, 2-hydroxy-5-methyl benzaldehyde, 2-hydroxy-5-bromo benzaldehyde, 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-1-naphthaldehyde to obtain L1–L5, respectively and complexed with nickel chloride. Single crystal X-ray diffraction studies of complexes 1 and 5 showed a distorted octahedral and distorted square-planar geometry, respectively around nickel atoms. The cyclic voltammetry of complexes 1–5 showed redox peaks near cathodic and anodic regions assignable to the Ni2+/Ni+ and Ni2+/Ni3+ redox couples, respectively. The binding studies of complexes with calf thymus DNA (ctDNA) showed an intercalation mode of binding. The nuclease activity of the complexes with pBR322 plasmid DNA showed efficient oxidative cleavage by the formation of singlet oxygen species in presence of H2O2. All nickel(II) complexes were found to have greater zone inhibition diameter when analyzed for antimicrobial property against four bacterial species and two human pathogenic fungal species.