1406-05-9

Basic information

• Product Name: Penicillin
• Synonyms: Penicillin (base and/or unspecified derivatives);Abbocillin vk;Anapenil;Apo-pen-vk;Asillin;Beapen;Calciopen;Cilacil
• CAS NO: 1406-05-9
• Molecular Formula: C16H20N2O3S
• Molecular Weight: 320.411
• EINECS: 215-794-6
• Mol File: 1406-05-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 739.2°C at 760 mmHg
• Flash Point: 400.9°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 6.59E-24mmHg at 25°C
• Refractive Index: 1.632
• CAS DataBase Reference: Penicillin(CAS DataBase Reference)
• NIST Chemistry Reference: Penicillin(1406-05-9)
• EPA Substance Registry System: Penicillin(1406-05-9)

Safety Data

• Hazardous Substances Data: 1406-05-9(Hazardous Substances Data)

Usage

Contact allergens

Penicillins can induce contact dermatitis, contact urticaria, and systemic and sometimes severe reactions. Occupational sensitivity to penicillins concerns health workers, workers in the pharmaceutical industry, and veterinaries, since these antibiotics are used by veterinarians and cattle breeders as medications and animal feed antibiotic. All penicillins contain the 6-aminopenicillanic acid moiety. Penicillins of G, V, A, and M groups are characterized by a specific C7 side chain. Cross-reactivity is possible between several penicillins, but is not systematic since both immediateand delayed-type sensitivity can implicate the 6-aminopenicillanic acid moiety, or be specific to the 7-side-chain.

Safety Profile

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by intravenous route. Human reproductive effects by ingestion: abortion. Human systemic effects by intramuscular route: dermatitis. Experimental reproductive effects. Has been implicated in aplastic anemia. When heated to decomposition it emits very toxic fumes of NOx and SOx

InChI:InChI=1/C14H21N3O6S/c1-14(2)9(13(22)23)17-10(19)8(11(17)24-14)16-7(18)5-3-4-6(15)12(20)21/h6,8-9,11H,3-5,15H2,1-2H3,(H,16,18)(H,20,21)(H,22,23)

Related news

Short communicationA safe and efficient technology of recovering nano glass from Penicillin (cas 1406-05-9) bottles of medical wastes09/29/2019

Waste penicillin bottles, a main component of medical wastes, have greatly produced in the world. Because of containing residual medicines and different microorganism, this kind of medical wastes is considered as hazardous waste. The unidentified microorganism inside waste penicillin bottles mak...detailed

Short reportImpact of Penicillin (cas 1406-05-9) allergy records on carbapenem prescribing: an observational retrospective cohort study09/28/2019

SummaryPenicillin allergy labels have been associated with second-line antibiotic prescribing. This study measured the impact of penicillin allergy labels on meropenem prescribing. Rates of meropenem prescribing were compared between patients with a penicillin allergy record and patients without...detailed

Fibronectin and laminin induce biofilm formation by Streptococcus uberis and decrease its Penicillin (cas 1406-05-9) susceptibility10/01/2019

The aim of this study was to determine the effect of fibronectin and laminin on the in vitro biofilm formation by Streptococcus uberis and the susceptibility to penicillin under planktonic and biofilm growth conditions. We observed that a high percentage (76.5%) of the S. uberis isolates was wea...detailed

Original ArticleComparing Direct Challenge to Penicillin (cas 1406-05-9) Skin Testing for the Outpatient Evaluation of Penicillin (cas 1406-05-9) Allergy: A Randomized Controlled Trial09/26/2019

BackgroundDirect challenge (DC) may be a safe and effective alternative to penicillin skin testing (PST) in low-risk patients.detailed

Original ArticlePatient and Primary Care Physician Perceptions of Penicillin (cas 1406-05-9) Allergy Testing and Subsequent Use of Penicillin (cas 1406-05-9)-Containing Antibiotics: A Qualitative Study09/25/2019

BackgroundRemoval of an inaccurate penicillin allergy record following testing allows patients to access first-line treatment for infections, and reduce the use of broad-spectrum antibiotics, which contribute to antibiotic resistance. However, it is seldom undertaken.detailed

Reported Knowledge and Management of Potential Penicillin (cas 1406-05-9) Allergy in Children09/24/2019

BackgroundPediatric emergency medicine (PEM) and primary care provider (PCP) providers are the most likely physicians to initially label a child as allergic to penicillin. Differences in knowledge and management of reported penicillin allergy between these 2 groups have not been well characterized.detailed