140633-32-5Relevant academic research and scientific papers
Process for preparing 1-aryl-4-oxopyrrolo ?3,2-c! quinoline derivatives
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, (2008/06/13)
The present invention relates to a process for preparing 1-aryl-4-oxopyrrolo?3,2-c!quinoline derivatives through reaction of 4-oxofuro?3,2-c! quinoline compounds with aniline compounds under mild conditions in a single step, wherein 1-aryl-4-oxopyrrolo?3,
A facile method for direct conversion of dihydrofuroquinolones to dihydropyrroloquinolones
Kim, Sung Soo,Cheon, Hyac Gyeong,Kang, Seung Kyu,Yum, Eul Kgun,Choi, Joong-Kwon
, p. 221 - 226 (2007/10/03)
A novel and efficient method is described for one-step conversion of dihydrofuroquinolones to dihydropyrroloquinolones in high yields under mild conditions.
Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 2. 1-Arylpyrroloquinolines: Effect of the 4-Substituent
Leach, Colin A.,Brown, Thomas H.,Ife, Robert J.,Keeling, David J.,Laing, Shiona M.,et al.
, p. 1845 - 1852 (2007/10/02)
Further work on compounds 1 has identified the 4-position as a site where substantial modifications are tolerated, leading to analogues which are more potent and less toxic than those described previously.The best compound in the series is 13a (SKandF 963
