140635-68-3

Upstream product

• 3282-10-8 methyl 3,5-dibromo-4-aminobenzoate 
• 619-45-4 4-methoxycarbonyl aniline 

Downstream Products

• 140635-70-7 3,5-dibromo-4-azidobenzoic acid 
• 119963-45-0 1-(p-isothiocyanatophenyl)-4-tert-butyl-2,6,7-trioxabicyclo<2.2.2>octane 
• 140635-72-9 4-Azido-3,5-dibromo-benzoyl chloride 
• 119963-49-4 1-(4-aminophenyl)-4-(t-butyl)-2,6,7-trioxabicyclo<2.2.2>octane 
• 140635-82-1 1-(4-amino-3,5-ditritiophenyl)-4-(t-butyl)-2,6,7-trioxabicyclo<2.2.2>octane 
• 140635-83-2 1-(4-isothicyana-3,5-ditritiotophenyl)-4-(t-butyl)-2,6,7-trioxabicyclo<2.2.2>octane 
• 140635-74-1 3-(t-butyl)-3-(3,5-dibromo-4-azidobenzoyloxymethyl)oxetane 
• 140635-76-3 1-(3,5-dibromo-4-azidophenyl)-4-(t-butyl)-2,6,7-trioxabicyclo<2.2.2>octane 

Relevant academic research and scientific papers

Preparation of polyfunctional aryl azides from aryl triazenes. A new synthesis of ellipticine, 9-methoxyellipticine, isoellipticine, and 7-carbethoxyisoellipticine

(Chemical Equation Presented) The preparation of polyfunctional aryl azides by the reaction of aryl triazenes with NaN3 in the presence of KHSO4 or BF3·OEt2/TFA (trifluoroacetic acid) has been described. A variety of functional groups (halides, esters, ketones, nitriles, aldehydes, and boronic esters) are tolerated under the Lewis acidic conditions. By using this methodology, the potent antitumor agents, ellipticine and 9-methoxyellipticine, have been synthesized. In addition, isoellipticine and a related derivative, 7-carbethoxyisoellipticine, were also prepared.

A PRACTICAL SYNTHESIS OF ISOTOPICALLY LABELLED 1-(4-ISOTHIOCYANATOPHENYL)-4-(t-BUTYL)-2,6,7-TRIOXABICYCLOOCTANE, A PROBE FOR THE BENZODIAZEPINE RECEPTOR-COUPLED CHLORIDE IONOPHORE

An efficient synthesis of high specific activity 1-(4-isothiocyanato-3,5-ditritiophenyl)-4-(t-butyl)-2,6,7-trioxabicyclooctane (-1), an affinity ligand for the benzodiazepine (BZ)-coupled γ-aminobutyric acid (GABA)-gated chloride channel, w